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Update on Horizon Scans of Genetic Tests Currently Available for Clinical Use in Cancers

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The Coverage and Analysis Group at the Centers for Medicare and Medicaid Services (CMS) is interested in an update report of genetic tests for cancer conditions and the accompanying database to serve as a ready reference for their internal discussions in this area as well as the source for decisions on future topics for systematic reviews. CMS requested that the Technology Assessment Program (TAP) of the Agency for Healthcare Research and Quality (AHRQ) conduct an update of genetic tests for cancer conditions that were identified since the 2006 horizon scan report on Genetic Testing for Cancer. AHRQ assigned this project to the Tufts Medical Center Evidence-based Practice Center (Contract Number: HHSA 290 2007 10055 I, Task Order #3, work assignment #3).

The main objective of this report is to provide succinct information along with a preliminary estimate on the amount of published literature available on each identified genetic test through grey literature search since 2006. Systematic review of selected tests will be the subject of future focused reviews. The contents in the database and in this report reflect the data of genetic tests that were obtained from manufacturers’ Web sites or other commercial Web sites, and should not be construed as definitive clinical evidence or as recommendations for their routine clinical use.

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