Additional Use Case: Clinical Trial Matching

COMPANY PLEDGE: We pledge to the CMS Interoperability Framework and to work collaboratively to close the clinical trial awareness and matching gap. We commit to establishing two complementary pathways: a compliant, claims-informed channel that routes population-level trial eligibility signals, including those identified within the CMS Virtual Research Data Center (VRDC), to treating providers, never directly to patients; and app- and EHR-based matching that integrates the ClinicalTrials.gov API and computable protocol standards (CDISC USDM, HL7 FHIR, ICH M11 ceSHarP) so patients and providers can discover relevant trials directly within care and app experiences. We believe trial discovery should no longer depend on individual clinician awareness alone, consistent with HHS's Operation TrialBlazer, helping to ensure every eligible patient has the opportunity to learn about and consider relevant clinical trials.